Impact of acute and chronic intermittent hypoxia on apnea severity
نویسندگان
چکیده
منابع مشابه
Impact of repeated daily exposure to intermittent hypoxia and mild sustained hypercapnia on apnea severity.
We examined whether exposure to intermittent hypoxia (IH) during wakefulness impacted on the apnea/hypopnea index (AHI) during sleep in individuals with sleep apnea. Participants were exposed to twelve 4-min episodes of hypoxia in the presence of sustained mild hypercapnia each day for 10 days. A control group was exposed to sustained mild hypercapnia for a similar duration. The intermittent hy...
متن کاملInfluence of obstructive sleep apnea on fatty liver disease: role of chronic intermittent hypoxia.
BACKGROUND Currently the common pathogenetic mechanisms in nonalcoholic fatty liver disease (NAFLD) and obstructive sleep apnea (OSA) are gaining increased attention. The aim of this study is to find out the influence of chronic intermittent hypoxemia and OSA related parameters to the severity of NAFLD. METHODS We examined the liver functions tests and ultrasonographic data of liver as well ...
متن کاملHyperlipidemia and lipid peroxidation are dependent on the severity of chronic intermittent hypoxia.
Obstructive sleep apnea (OSA) is characterized by chronic intermittent hypoxia (CIH) and associated with dysregulation of lipid metabolisms and atherosclerosis. Causal relationships between OSA and metabolic abnormalities have not been established because of confounding effects of underlying obesity. The goal of the study was to determine if CIH causes lipid peroxidation and dyslipidemia in the...
متن کاملHIGHLIGHTED TOPIC Physiology and Pathophysiology of Sleep Apnea Acute and chronic cardiovascular effects of intermittent hypoxia in C57BL/6J mice
Campen, M. J., L. A. Shimoda, and, C. P. O’Donnell. Acute and chronic cardiovascular effects of intermittent hypoxia in C57BL/6J mice. J Appl Physiol 99: 2028–2035, 2005. First published July 7, 2005; doi:10.1152/japplphysiol.00411.2005.—We investigated the effects of 1) acute hypoxia and 2) 5 wk of chronic intermittent hypoxia (IH) on the systemic and pulmonary circulations of C57BL/6J mice. M...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2010
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.24.1_supplement.799.28